GO Annotations Graph

• Symbol: Klrk1
• Name: killer cell lectin-like receptor subfamily K, member 1
• ID: MGI:1196250

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030246	carbohydrate binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:88981
Molecular Function	GO:0019900	kinase binding	IPI	J:92687
Molecular Function	GO:0042288	MHC class I protein binding	IPI	J:131505
Molecular Function	GO:0042288	MHC class I protein binding	IPI	J:131505
Molecular Function	GO:0032394	MHC class Ib receptor activity	IMP	J:82077
Molecular Function	GO:0005515	protein binding	IPI	J:248465
Molecular Function	GO:0005515	protein binding	IPI	J:92687
Molecular Function	GO:0005515	protein binding	IPI	J:88981
Molecular Function	GO:0005515	protein binding	IPI	J:82077
Molecular Function	GO:0005515	protein binding	IPI	J:82077
Molecular Function	GO:0005515	protein binding	IPI	J:82077
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:92687
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:88981
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:88001
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:197348
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:113553
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:82077
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87433
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2326808
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:88001
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IDA	J:88001
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0030101	natural killer cell activation	IPI	J:131505
Biological Process	GO:0030101	natural killer cell activation	IPI	J:131505
Biological Process	GO:0030101	natural killer cell activation	IMP	J:82077
Biological Process	GO:0030101	natural killer cell activation	IPI	J:131505
Biological Process	GO:0006809	nitric oxide biosynthetic process	IDA	J:82077
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0030887	positive regulation of myeloid dendritic cell activation	ISO	J:155856
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IDA	J:92687
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IBA	J:265628
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IMP	J:82077
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	ISO	J:155856
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IDA	J:82077
Biological Process	GO:0032729	positive regulation of type II interferon production	IDA	J:82077
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway	IMP	J:82077
Biological Process	GO:0032609	type II interferon production	IDA	J:82077