GO Annotations Graph

• Symbol: Eif6
• Name: eukaryotic translation initiation factor 6
• ID: MGI:1196288

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043023	ribosomal large subunit binding	IBA	J:265628
Molecular Function	GO:0043022	ribosome binding	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005882	intermediate filament	IDA	J:44335
Cellular Component	GO:0005638	lamin filament	IDA	J:44335
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0030687	preribosome, large subunit precursor	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:263419
Cellular Component	GO:0045202	synapse	EXP	J:263419
Biological Process	GO:1902626	assembly of large subunit precursor of preribosome	IBA	J:265628
Biological Process	GO:0042256	cytosolic ribosome assembly	ISO	J:164563
Biological Process	GO:0000460	maturation of 5.8S rRNA	IBA	J:265628
Biological Process	GO:0000470	maturation of LSU-rRNA	IBA	J:265628
Biological Process	GO:0035195	miRNA-mediated gene silencing	ISO	J:164563
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ISO	J:164563
Biological Process	GO:0045727	positive regulation of translation	IMP	J:226984
Biological Process	GO:0042304	regulation of fatty acid biosynthetic process	IMP	J:226984
Biological Process	GO:0006110	regulation of glycolytic process	IMP	J:226984
Biological Process	GO:0045652	regulation of megakaryocyte differentiation	IMP	J:232943
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	IMP	J:232943
Biological Process	GO:0032868	response to insulin	IMP	J:226984
Biological Process	GO:0000054	ribosomal subunit export from nucleus	IBA	J:265628
Biological Process	GO:0042254	ribosome biogenesis	IEA	J:60000
Biological Process	GO:0006412	translation	IEA	J:60000
Biological Process	GO:0006413	translational initiation	IEA	J:60000