GO Annotations Graph

• Symbol: Nus1
• Name: NUS1 dehydrodolichyl diphosphate synthase subunit
• ID: MGI:1196365

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045547	dehydrodolichyl diphosphate synthase activity	ISO	J:164563
Molecular Function	GO:0045547	dehydrodolichyl diphosphate synthase activity	IBA	J:265628
Molecular Function	GO:0004659	prenyltransferase activity	IMP	J:215785
Molecular Function	GO:0004659	prenyltransferase activity	ISO	J:73065
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEA	J:72247
Cellular Component	GO:1904423	dehydrodolichyl diphosphate synthase complex	ISO	J:164563
Cellular Component	GO:1904423	dehydrodolichyl diphosphate synthase complex	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:73065
Cellular Component	GO:0016020	membrane	IMP	J:215785
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:215785
Biological Process	GO:0019408	dolichol biosynthetic process	IBA	J:265628
Biological Process	GO:0019408	dolichol biosynthetic process	ISO	J:73065
Biological Process	GO:0006489	dolichyl diphosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	ISO	J:164563
Biological Process	GO:0006486	protein glycosylation	IBA	J:265628
Biological Process	GO:0035268	protein mannosylation	IMP	J:215785
Biological Process	GO:0032383	regulation of intracellular cholesterol transport	ISO	J:73065
Biological Process	GO:0032383	regulation of intracellular cholesterol transport	IMP	J:152386
Biological Process	GO:0055092	sterol homeostasis	IMP	J:152386
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	ISO	J:164563