GO Annotations Graph

• Symbol: Pole
• Name: polymerase (DNA directed), epsilon
• ID: MGI:1196391

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	ISO	J:155856
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	ISO	J:164563
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:60000
Molecular Function	GO:0008310	single-stranded DNA 3'-5' DNA exonuclease activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0008622	epsilon DNA polymerase complex	ISO	J:164563
Cellular Component	GO:0008622	epsilon DNA polymerase complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0006287	base-excision repair, gap-filling	ISO	J:164563
Biological Process	GO:0006287	base-excision repair, gap-filling	IBA	J:265628
Biological Process	GO:0071897	DNA biosynthetic process	ISO	J:155856
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:72247
Biological Process	GO:0006260	DNA replication	ISO	J:164563
Biological Process	GO:0045004	DNA replication proofreading	IBA	J:265628
Biological Process	GO:0000731	DNA synthesis involved in DNA repair	ISO	J:164563
Biological Process	GO:0006261	DNA-templated DNA replication	ISO	J:164563
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0006272	leading strand elongation	IBA	J:265628
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0006297	nucleotide-excision repair, DNA gap filling	ISO	J:164563
Biological Process	GO:0006297	nucleotide-excision repair, DNA gap filling	IBA	J:265628