GO Annotations Graph

• Symbol: Pla2g4c
• Name: phospholipase A2, group IVC (cytosolic, calcium-independent)
• ID: MGI:1196403

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	IBA	J:265628
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004622	lysophospholipase activity	ISO	J:164563
Molecular Function	GO:0008374	O-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0102545	phosphatidyl phospholipase B activity	IEA	J:72245
Molecular Function	GO:0004623	phospholipase A2 activity	IEA	J:72245
Molecular Function	GO:0004620	phospholipase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005938	cell cortex	IDA	J:99396
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	IDA	J:99396
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	IDA	J:99396
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0046475	glycerophospholipid catabolic process	ISO	J:164563
Biological Process	GO:0046475	glycerophospholipid catabolic process	IBA	J:265628
Biological Process	GO:0140042	lipid droplet formation	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0036151	phosphatidylcholine acyl-chain remodeling	ISO	J:164563
Biological Process	GO:0036152	phosphatidylethanolamine acyl-chain remodeling	ISO	J:164563
Biological Process	GO:0009395	phospholipid catabolic process	IEA	J:72247
Biological Process	GO:0006663	platelet activating factor biosynthetic process	ISO	J:164563