GO Annotations Graph

• Symbol: Scarb2
• Name: scavenger receptor class B, member 2
• ID: MGI:1196458

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038024	cargo receptor activity	IMP	J:131449
Molecular Function	GO:0038024	cargo receptor activity	ISO	J:164563
Molecular Function	GO:0015485	cholesterol binding	IDA	J:258398
Molecular Function	GO:0019899	enzyme binding	IPI	J:131449
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0031210	phosphatidylcholine binding	IDA	J:258398
Molecular Function	GO:0001786	phosphatidylserine binding	IDA	J:258398
Molecular Function	GO:0005515	protein binding	IPI	J:269546
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:258398
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0051087	protein-folding chaperone binding	IPI	J:269546
Molecular Function	GO:0005044	scavenger receptor activity	IDA	J:258398
Molecular Function	GO:0005044	scavenger receptor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0030666	endocytic vesicle membrane	IDA	J:258398
Cellular Component	GO:0043202	lysosomal lumen	IDA	J:131449
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:131449
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0005764	lysosome	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IDA	J:258398
Biological Process	GO:0015917	aminophospholipid transport	IDA	J:258398
Biological Process	GO:0010467	gene expression	IMP	J:121998
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0006622	protein targeting to lysosome	ISO	J:164563
Biological Process	GO:0006622	protein targeting to lysosome	IMP	J:131449
Biological Process	GO:0006622	protein targeting to lysosome	IBA	J:265628
Biological Process	GO:0006898	receptor-mediated endocytosis	IDA	J:258398
Biological Process	GO:0006898	receptor-mediated endocytosis	IBA	J:265628
Biological Process	GO:0043470	regulation of carbohydrate catabolic process	IMP	J:131449
Biological Process	GO:0043470	regulation of carbohydrate catabolic process	ISO	J:164563
Biological Process	GO:1905123	regulation of glucosylceramidase activity	IMP	J:216676
Biological Process	GO:1905123	regulation of glucosylceramidase activity	IBA	J:265628
Biological Process	GO:0007605	sensory perception of sound	IMP	J:121998