GO Annotations Graph

• Symbol: Ccn4
• Name: cellular communication network factor 4
• ID: MGI:1197008

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IMP	J:273517
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Biological Process	GO:0060348	bone development	IMP	J:273609
Biological Process	GO:0060348	bone development	IMP	J:233817
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0042593	glucose homeostasis	IMP	J:273535
Biological Process	GO:0060548	negative regulation of cell death	IBA	J:265628
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	IMP	J:273609
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:273517
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:273609
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:233817
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IMP	J:233817
Biological Process	GO:0090303	positive regulation of wound healing	IMP	J:264594
Biological Process	GO:0001817	regulation of cytokine production	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000