GO Annotations Graph

• Symbol: Pknox1
• Name: Pbx/knotted 1 homeobox
• ID: MGI:1201409

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0003677	DNA binding	IDA	J:45106
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:55892
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:55892
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0005515	protein binding	IPI	J:56023
Molecular Function	GO:0005515	protein binding	IPI	J:45106
Molecular Function	GO:0005515	protein binding	IPI	J:56023
Molecular Function	GO:0005515	protein binding	IPI	J:56023
Molecular Function	GO:0005515	protein binding	IPI	J:89598
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:119671
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:56023
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:89598
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:133010
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:89962
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621012
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	IDA	J:111418
Cellular Component	GO:0005634	nucleus	IDA	J:119671
Cellular Component	GO:0005634	nucleus	IDA	J:111418
Cellular Component	GO:0005634	nucleus	IDA	J:89962
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:45106
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:55892
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:119671
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:56023
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:89598
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IMP	J:111418
Biological Process	GO:0043010	camera-type eye development	IMP	J:111418
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:111418
Biological Process	GO:0030097	hemopoiesis	IMP	J:127523
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAS	J:133010
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:56023
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	TAS	J:133010
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:55892
Biological Process	GO:0030217	T cell differentiation	IMP	J:103769