GO Annotations Graph

• Symbol: Cer1
• Name: cerberus 1, DAN family BMP antagonist
• ID: MGI:1201414

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0036122	BMP binding	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0016015	morphogen activity	ISO	J:164563
Molecular Function	GO:0016015	morphogen activity	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:62082
Cellular Component	GO:0005576	extracellular region	IDA	J:44900
Cellular Component	GO:0005615	extracellular space	IDA	J:62082
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0009948	anterior/posterior axis specification	IGI	J:132584
Biological Process	GO:0009948	anterior/posterior axis specification	IGI	J:90040
Biological Process	GO:0009948	anterior/posterior axis specification	IDA	J:90040
Biological Process	GO:0009952	anterior/posterior pattern specification	IDA	J:46377
Biological Process	GO:0030282	bone mineralization	ISO	J:164563
Biological Process	GO:0042074	cell migration involved in gastrulation	IGI	J:90040
Biological Process	GO:0008283	cell population proliferation	IGI	J:90040
Biological Process	GO:0008283	cell population proliferation	IGI	J:90040
Biological Process	GO:0071276	cellular response to cadmium ion	IDA	J:297615
Biological Process	GO:0048263	determination of dorsal identity	ISO	J:164563
Biological Process	GO:0061371	determination of heart left/right asymmetry	IBA	J:265628
Biological Process	GO:0007369	gastrulation	IGI	J:132584
Biological Process	GO:0003419	growth plate cartilage chondrocyte proliferation	IEP	J:182485
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	IDA	J:62082
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:46377
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IDA	J:44900
Biological Process	GO:0008285	negative regulation of cell population proliferation	IGI	J:90040
Biological Process	GO:2000381	negative regulation of mesoderm development	IDA	J:62082
Biological Process	GO:2000381	negative regulation of mesoderm development	ISO	J:164563
Biological Process	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	IBA	J:265628
Biological Process	GO:0007399	nervous system development	ISO	J:164563
Biological Process	GO:0035582	sequestering of BMP in extracellular matrix	IDA	J:62082
Biological Process	GO:0035582	sequestering of BMP in extracellular matrix	ISO	J:164563
Biological Process	GO:0035582	sequestering of BMP in extracellular matrix	IBA	J:265628
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IBA	J:265628
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0001657	ureteric bud development	IMP	J:180958