Eomes GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Eomes
eomesodermin
MGI:1201683

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:176969
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:266522
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:226614
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:160495
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:190269
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:168146
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:190269
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:113146
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9754479
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756660
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756665
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756678
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9756684
Cellular Component	GO:0005634	nucleus	IDA	J:150768
Cellular Component	GO:0005634	nucleus	IDA	J:99440
Cellular Component	GO:0005634	nucleus	IDA	J:99440
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:99440
Cellular Component	GO:0005634	nucleus	IDA	J:99440
Cellular Component	GO:0005634	nucleus	IDA	J:197573
Cellular Component	GO:0005634	nucleus	IDA	J:215584
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:266522
Biological Process	GO:0001824	blastocyst development	IMP	J:98502
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0010002	cardioblast differentiation	IMP	J:176969
Biological Process	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	IDA	J:154842
Biological Process	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	ISO	J:164563
Biological Process	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IMP	J:98502
Biological Process	GO:0030154	cell differentiation	IMP	J:60897
Biological Process	GO:0060706	cell differentiation involved in embryonic placenta development	IMP	J:60897
Biological Process	GO:0021987	cerebral cortex development	IMP	J:266522
Biological Process	GO:0021895	cerebral cortex neuron differentiation	IDA	J:144650
Biological Process	GO:0021796	cerebral cortex regionalization	IMP	J:266522
Biological Process	GO:0021796	cerebral cortex regionalization	IMP	J:196080
Biological Process	GO:0006338	chromatin remodeling	IMP	J:266522
Biological Process	GO:0080111	DNA demethylation	IMP	J:266522
Biological Process	GO:0006306	DNA methylation	IMP	J:266522
Biological Process	GO:0001706	endoderm formation	IMP	J:131055
Biological Process	GO:0001706	endoderm formation	IMP	J:176969
Biological Process	GO:0001706	endoderm formation	IMP	J:168146
Biological Process	GO:0001714	endodermal cell fate specification	IBA	J:265628
Biological Process	GO:0001714	endodermal cell fate specification	IMP	J:168146
Biological Process	GO:0007369	gastrulation	IEA	J:60000
Biological Process	GO:0010467	gene expression	IMP	J:266522
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001707	mesoderm formation	IBA	J:265628
Biological Process	GO:0001707	mesoderm formation	IMP	J:60897
Biological Process	GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	IMP	J:131055
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	IDA	J:190269
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:190269
Biological Process	GO:0022008	neurogenesis	IMP	J:138764
Biological Process	GO:0030182	neuron differentiation	IMP	J:266522
Biological Process	GO:0030182	neuron differentiation	IMP	J:138764
Biological Process	GO:0001764	neuron migration	IMP	J:266522
Biological Process	GO:0021772	olfactory bulb development	IMP	J:148764
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:168146
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IMP	J:168146
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:154112
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:160495
Biological Process	GO:0001829	trophectodermal cell differentiation	IDA	J:104800
Biological Process	GO:0001829	trophectodermal cell differentiation	IGI	J:104800
Biological Process	GO:0032609	type II interferon production	IDA	J:160369

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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