GO Annotations Graph

• Symbol: Tapbp
• Name: TAP binding protein
• ID: MGI:1201689

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:90842
Molecular Function	GO:0062061	TAP complex binding	ISO	J:164563
Molecular Function	GO:0062061	TAP complex binding	IBA	J:265628
Molecular Function	GO:0046978	TAP1 binding	ISO	J:164563
Molecular Function	GO:0046979	TAP2 binding	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:164563
Cellular Component	GO:0042824	MHC class I peptide loading complex	ISO	J:155856
Cellular Component	GO:0042824	MHC class I peptide loading complex	IBA	J:265628
Cellular Component	GO:0030670	phagocytic vesicle membrane	TAS	Reactome:R-NUL-1236962
Cellular Component	GO:0005886	plasma membrane	TAS	J:64177
Cellular Component	GO:0061779	Tapasin-ERp57 complex	ISO	J:164563
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	IEA	J:72247
Biological Process	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	IDA	J:50012
Biological Process	GO:0006952	defense response	IMP	J:64177
Biological Process	GO:0002397	MHC class I protein complex assembly	IBA	J:265628
Biological Process	GO:0002398	MHC class Ib protein complex assembly	ISO	J:164563
Biological Process	GO:0002502	peptide antigen assembly with MHC class I protein complex	ISO	J:164563
Biological Process	GO:0050823	peptide antigen stabilization	IMP	J:113970
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0010468	regulation of gene expression	ISO	J:164563
Biological Process	GO:0061635	regulation of protein complex stability	ISO	J:164563