GO Annotations Graph

• Symbol: Pik3c2a
• Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
• ID: MGI:1203729

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	IDA	J:296091
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	ISO	J:164563
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	IBA	J:265628
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	IDA	J:33394
Molecular Function	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	ISO	J:164563
Molecular Function	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0030276	clathrin binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0035004	phosphatidylinositol 3-kinase activity	IEA	J:72247
Molecular Function	GO:0035091	phosphatidylinositol binding	IEA	J:72247
Molecular Function	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	IEA	J:72245
Molecular Function	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005942	phosphatidylinositol 3-kinase complex	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Biological Process	GO:1905037	autophagosome organization	IGI	J:209036
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0009267	cellular response to starvation	IGI	J:209036
Biological Process	GO:0006897	endocytosis	ISO	J:164563
Biological Process	GO:0006887	exocytosis	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0046834	lipid phosphorylation	IDA	J:33394
Biological Process	GO:0016236	macroautophagy	IGI	J:209036
Biological Process	GO:0071583	negative regulation of zinc ion transmembrane transport	IMP	J:204751
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	IEA	J:72247
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	IDA	J:33394
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	IBA	J:265628
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	IGI	J:209036
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	IEA	J:72247
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	ISO	J:164563