GO Annotations Graph

• Symbol: Sgpl1
• Name: sphingosine phosphate lyase 1
• ID: MGI:1261415

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016830	carbon-carbon lyase activity	IEA	J:72247
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0030170	pyridoxal phosphate binding	IEA	J:72247
Molecular Function	GO:0008117	sphinganine-1-phosphate aldolase activity	ISO	J:164563
Molecular Function	GO:0008117	sphinganine-1-phosphate aldolase activity	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:242932
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0008209	androgen metabolic process	IMP	J:142042
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0019752	carboxylic acid metabolic process	IEA	J:72247
Biological Process	GO:0006672	ceramide metabolic process	ISO	J:164563
Biological Process	GO:0008210	estrogen metabolic process	IMP	J:142042
Biological Process	GO:0060325	face morphogenesis	IMP	J:117491
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0008585	female gonad development	IMP	J:142042
Biological Process	GO:0010761	fibroblast migration	IMP	J:117491
Biological Process	GO:0030097	hemopoiesis	IMP	J:117491
Biological Process	GO:0001822	kidney development	IMP	J:117491
Biological Process	GO:0033327	Leydig cell differentiation	IMP	J:142042
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0001553	luteinization	IMP	J:142042
Biological Process	GO:0006807	nitrogen compound metabolic process	IMP	J:117491
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	IMP	J:117491
Biological Process	GO:0009791	post-embryonic development	IMP	J:117491
Biological Process	GO:0040014	regulation of multicellular organism growth	IMP	J:117491
Biological Process	GO:0060021	roof of mouth development	IMP	J:117491
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:117491
Biological Process	GO:0007283	spermatogenesis	IMP	J:142042
Biological Process	GO:0030149	sphingolipid catabolic process	ISO	J:164563
Biological Process	GO:0030149	sphingolipid catabolic process	IBA	J:265628
Biological Process	GO:0006665	sphingolipid metabolic process	IEA	J:60000
Biological Process	GO:0001570	vasculogenesis	IMP	J:117491