GO Annotations Graph

• Symbol: Suz12
• Name: SUZ12 polycomb repressive complex 2 subunit
• ID: MGI:1261758

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:109525
Molecular Function	GO:0003682	chromatin binding	IDA	J:218234
Molecular Function	GO:0003682	chromatin binding	IDA	J:109525
Molecular Function	GO:0003682	chromatin binding	IDA	J:109525
Molecular Function	GO:0003682	chromatin binding	IDA	J:109525
Molecular Function	GO:0003682	chromatin binding	IDA	J:109525
Molecular Function	GO:0031490	chromatin DNA binding	IBA	J:265628
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:134766
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0042054	histone methyltransferase activity	ISO	J:73065
Molecular Function	GO:0106222	lncRNA binding	IPI	J:256017
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:227373
Molecular Function	GO:0005515	protein binding	IPI	J:157724
Molecular Function	GO:0005515	protein binding	IPI	J:200240
Molecular Function	GO:0005515	protein binding	IPI	J:158991
Molecular Function	GO:0005515	protein binding	IPI	J:175603
Molecular Function	GO:0005515	protein binding	IPI	J:198821
Molecular Function	GO:0005515	protein binding	IPI	J:198819
Molecular Function	GO:0005515	protein binding	IPI	J:206847
Molecular Function	GO:0005515	protein binding	IPI	J:157630
Molecular Function	GO:0005515	protein binding	IPI	J:157630
Molecular Function	GO:0005515	protein binding	IPI	J:240581
Molecular Function	GO:0005515	protein binding	IPI	J:157630
Molecular Function	GO:0003723	RNA binding	IPI	J:225861
Molecular Function	GO:0003723	RNA binding	IPI	J:207590
Molecular Function	GO:0003723	RNA binding	IPI	J:188128
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:206154
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:165919
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Cellular Component	GO:0005677	chromatin silencing complex	IDA	J:228292
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:196211
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157630
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:183475
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157724
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157068
Cellular Component	GO:0035098	ESC/E(Z) complex	IBA	J:265628
Cellular Component	GO:0035098	ESC/E(Z) complex	ISO	J:73065
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:281161
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619436
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619437
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619438
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810138
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810150
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810170
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:134766
Cellular Component	GO:0032993	protein-DNA complex	IDA	J:134766
Cellular Component	GO:1990904	ribonucleoprotein complex	IPI	J:256017
Cellular Component	GO:0016586	RSC-type complex	IBA	J:265628
Cellular Component	GO:0001739	sex chromatin	IDA	J:94519
Biological Process	GO:0008283	cell population proliferation	IMP	J:93307
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IMP	J:104662
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	IMP	J:240642
Biological Process	GO:0140718	facultative heterochromatin formation	IDA	J:157630
Biological Process	GO:0140718	facultative heterochromatin formation	IDA	J:157724
Biological Process	GO:0010467	gene expression	IGI	J:256017
Biological Process	GO:0098532	histone H3-K27 trimethylation	ISO	J:155856
Biological Process	GO:0045596	negative regulation of cell differentiation	ISO	J:164563
Biological Process	GO:0032682	negative regulation of chemokine production	ISO	J:155856
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:109525
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	ISO	J:155856
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:256017
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:93307