GO Annotations Graph

• Symbol: Cyp2j6
• Name: cytochrome P450, family 2, subfamily j, polypeptide 6
• ID: MGI:1270148

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008405	arachidonic acid 11,12-epoxygenase activity	ISO	J:164563
Molecular Function	GO:0008404	arachidonic acid 14,15-epoxygenase activity	ISO	J:164563
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	ISO	J:164563
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	IMP	J:101489
Molecular Function	GO:0008391	arachidonic acid monooxygenase activity	ISO	J:155856
Molecular Function	GO:0070330	aromatase activity	IEA	J:72245
Molecular Function	GO:0020037	heme binding	IBA	J:265628
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0016853	isomerase activity	ISO	J:164563
Molecular Function	GO:0071614	linoleic acid epoxygenase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:72247
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:60000
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:158229
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:158229
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0019369	arachidonic acid metabolic process	ISO	J:155856
Biological Process	GO:0019373	epoxygenase P450 pathway	ISO	J:164563
Biological Process	GO:0006690	icosanoid metabolic process	ISO	J:164563
Biological Process	GO:0043651	linoleic acid metabolic process	ISO	J:164563
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	ISO	J:155856
Biological Process	GO:0006082	organic acid metabolic process	IBA	J:265628
Biological Process	GO:1903055	positive regulation of extracellular matrix organization	ISO	J:155856
Biological Process	GO:0045722	positive regulation of gluconeogenesis	ISO	J:155856
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0001523	retinoid metabolic process	ISO	J:155856
Biological Process	GO:0006805	xenobiotic metabolic process	IBA	J:265628