GO Annotations Graph

• Symbol: Rps6kb1
• Name: ribosomal protein S6 kinase, polypeptide 1
• ID: MGI:1270849

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:163623
Molecular Function	GO:0004672	protein kinase activity	ISO	J:155856
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IDA	J:91846
Molecular Function	GO:0004672	protein kinase activity	IMP	J:91846
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	ISO	J:199676
Molecular Function	GO:0004711	ribosomal protein S6 kinase activity	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326636
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:326636
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IDA	J:161036
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0001662	behavioral fear response	IGI	J:212538
Biological Process	GO:0001662	behavioral fear response	IGI	J:212538
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	IDA	J:141655
Biological Process	GO:0071363	cellular response to growth factor stimulus	ISO	J:164563
Biological Process	GO:0032869	cellular response to insulin stimulus	IBA	J:265628
Biological Process	GO:0032869	cellular response to insulin stimulus	IGI	J:211147
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:212538
Biological Process	GO:0071346	cellular response to type II interferon	IMP	J:244749
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0007281	germ cell development	IDA	J:78328
Biological Process	GO:0044539	long-chain fatty acid import into cell	IMP	J:244749
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:326636
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:326636
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:161036
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	IMP	J:161036
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IMP	J:244749
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0048633	positive regulation of skeletal muscle tissue growth	ISO	J:155856
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0045727	positive regulation of translation	ISO	J:164563
Biological Process	GO:0045948	positive regulation of translational initiation	ISO	J:164563
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:91846
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:91846
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:91846
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:91846
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IMP	J:91846
Biological Process	GO:0006468	protein phosphorylation	IDA	J:91846
Biological Process	GO:0046324	regulation of glucose import	ISO	J:155856
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0032868	response to insulin	ISO	J:155856
Biological Process	GO:0031667	response to nutrient levels	ISO	J:164563
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0031929	TOR signaling	ISO	J:164563
Biological Process	GO:0038202	TORC1 signaling	ISO	J:285299