Robo1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Robo1
roundabout guidance receptor 1
MGI:1274781

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0030275	LRR domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:156034
Molecular Function	GO:0005515	protein binding	IPI	J:153134
Cellular Component	GO:0030673	axolemma	IDA	J:89438
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985822
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985829
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010235
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010950
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9011080
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9014847
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0035904	aorta development	IGI	J:244269
Biological Process	GO:0003180	aortic valve morphogenesis	IGI	J:244269
Biological Process	GO:0007411	axon guidance	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IMP	J:89780
Biological Process	GO:0007411	axon guidance	IMP	J:89438
Biological Process	GO:0016199	axon midline choice point recognition	IGI	J:143208
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0003272	endocardial cushion formation	IGI	J:244269
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0060763	mammary duct terminal end bud growth	IMP	J:106011
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:141875
Biological Process	GO:0070100	negative regulation of chemokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:244269
Biological Process	GO:0033600	negative regulation of mammary gland epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0050925	negative regulation of negative chemotaxis	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0021891	olfactory bulb interneuron development	IGI	J:119469
Biological Process	GO:0003148	outflow tract septum morphogenesis	IGI	J:244269
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	IDA	J:244269
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0003184	pulmonary valve morphogenesis	IGI	J:244269
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0035385	Roundabout signaling pathway	ISO	J:164563
Biological Process	GO:0003281	ventricular septum development	IMP	J:222159
Biological Process	GO:0060412	ventricular septum morphogenesis	IGI	J:244269

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24