Cldn1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cldn1
claudin 1
MGI:1276109

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:94758
Molecular Function	GO:0005515	protein binding	IPI	J:58914
Molecular Function	GO:0005515	protein binding	IPI	J:94758
Molecular Function	GO:0005515	protein binding	IPI	J:73641
Molecular Function	GO:0005515	protein binding	IPI	J:73641
Molecular Function	GO:0005198	structural molecule activity	IEA	J:72247
Molecular Function	GO:0001618	virus receptor activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:159723
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:75447
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:48635
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:164563
Cellular Component	GO:0005923	bicellular tight junction	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:200284
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:104866
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:107229
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:181271
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:97223
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:181271
Cellular Component	GO:0030054	cell junction	IDA	J:219071
Cellular Component	GO:0030054	cell junction	TAS	Reactome:R-MMU-420000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:280103
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:181271
Cellular Component	GO:0016020	membrane	NAS	J:48635
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:75447
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-420000
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:97223
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Cellular Component	GO:0070160	tight junction	IDA	J:280385
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	IBA	J:265628
Biological Process	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	IDA	J:113790
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0034331	cell junction maintenance	IMP	J:280103
Biological Process	GO:0045216	cell-cell junction organization	ISO	J:73065
Biological Process	GO:0008065	establishment of blood-nerve barrier	ISO	J:155856
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	ISO	J:155856
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:75447
Biological Process	GO:0061436	establishment of skin barrier	ISO	J:164563
Biological Process	GO:1903348	positive regulation of bicellular tight junction assembly	ISO	J:155856
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	ISO	J:164563
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:0051259	protein complex oligomerization	ISO	J:164563
Biological Process	GO:0070673	response to interleukin-18	ISO	J:155856
Biological Process	GO:0061772	xenobiotic transport across blood-nerve barrier	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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