GO Annotations Graph

• Symbol: Ncoa3
• Name: nuclear receptor coactivator 3
• ID: MGI:1276535

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	IDA	J:104056
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:192962
Molecular Function	GO:0004402	histone acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:155856
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0016922	nuclear receptor binding	IBA	J:265628
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:155856
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IBA	J:265628
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IDA	J:192962
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:239004
Molecular Function	GO:0005515	protein binding	IPI	J:188268
Molecular Function	GO:0005515	protein binding	IPI	J:222684
Molecular Function	GO:0005515	protein binding	IPI	J:230369
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000993	RNA polymerase II complex binding	IDA	J:188268
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:239004
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:188268
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:192962
Biological Process	GO:0043697	cell dedifferentiation	IMP	J:188268
Biological Process	GO:0071392	cellular response to estradiol stimulus	ISO	J:164563
Biological Process	GO:0032870	cellular response to hormone stimulus	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:192962
Biological Process	GO:0060713	labyrinthine layer morphogenesis	IGI	J:182838
Biological Process	GO:0060744	mammary gland branching involved in thelarche	IMP	J:62748
Biological Process	GO:0035264	multicellular organism growth	IMP	J:62724
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:2000737	negative regulation of stem cell differentiation	IMP	J:192962
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:155856
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:192962
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	ISO	J:155856
Biological Process	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	ISO	J:155856
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	ISO	J:164563
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	IMP	J:188268
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:192962
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:2000035	regulation of stem cell division	IMP	J:188268
Biological Process	GO:2000035	regulation of stem cell division	IMP	J:192962
Biological Process	GO:2000036	regulation of stem cell population maintenance	IMP	J:192962
Biological Process	GO:0072091	regulation of stem cell proliferation	IMP	J:192962