GO Annotations Graph

• Symbol: Nsd1
• Name: nuclear receptor-binding SET-domain protein 1
• ID: MGI:1276545

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:93510
Molecular Function	GO:0140954	histone H3K36 dimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IDA	J:83923
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164569
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	IDA	J:83923
Molecular Function	GO:0042054	histone methyltransferase activity	IDA	J:83923
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	IPI	J:48279
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	IPI	J:48279
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	IPI	J:48279
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	IPI	J:48279
Molecular Function	GO:0005515	protein binding	IPI	J:91024
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164569
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	IDA	J:48279
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:48279
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0035097	histone methyltransferase complex	IC	J:83923
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:130872
Cellular Component	GO:0005634	nucleus	IC	J:91024
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0001702	gastrulation with mouth forming second	IMP	J:83923
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:48279
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:48279
Biological Process	GO:0033135	regulation of peptidyl-serine phosphorylation	ISO	J:164569
Biological Process	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	ISO	J:164569