GO Annotations Graph

• Symbol: Nsd2
• Name: nuclear receptor binding SET domain protein 2
• ID: MGI:1276574

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:150360
Molecular Function	GO:0003682	chromatin binding	IDA	J:150360
Molecular Function	GO:0003682	chromatin binding	IDA	J:150360
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0140954	histone H3K36 dimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0140955	histone H3K36 trimethyltransferase activity	IDA	J:150360
Molecular Function	GO:0042054	histone methyltransferase activity	IDA	J:191725
Molecular Function	GO:0042054	histone methyltransferase activity	IDA	J:150360
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:150360
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:191725
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:150360
Biological Process	GO:0003289	atrial septum primum morphogenesis	IMP	J:150360
Biological Process	GO:0003290	atrial septum secundum morphogenesis	IMP	J:150360
Biological Process	GO:0060348	bone development	IMP	J:150360
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0016570	histone modification	IDA	J:150360
Biological Process	GO:0003149	membranous septum morphogenesis	IMP	J:150360
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:150360
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	IMP	J:191725
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:191725
Biological Process	GO:2001032	regulation of double-strand break repair via nonhomologous end joining	IMP	J:191725
Biological Process	GO:0070201	regulation of establishment of protein localization	IMP	J:191725