GO Annotations Graph

• Symbol: Ldlrad4
• Name: low density lipoprotein receptor class A domain containing 4
• ID: MGI:1277150

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070412	R-SMAD binding	ISO	J:164563
Molecular Function	GO:0070412	R-SMAD binding	IBA	J:265628
Cellular Component	GO:0031901	early endosome membrane	ISO	J:164563
Cellular Component	GO:0031901	early endosome membrane	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0000139	Golgi membrane	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0009968	negative regulation of signal transduction	IEA	J:60000
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	ISO	J:164563
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	IBA	J:265628
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IMP	J:213178
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IBA	J:265628