Atg5 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Atg5
autophagy related 5
MGI:1277186

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019776	Atg8 ligase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:83346
Molecular Function	GO:0005515	protein binding	IPI	J:289080
Molecular Function	GO:0005515	protein binding	IPI	J:70539
Molecular Function	GO:0005515	protein binding	IPI	J:83346
Molecular Function	GO:0005515	protein binding	IPI	J:164739
Molecular Function	GO:0005515	protein binding	IPI	J:80842
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	ISO	J:164563
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	IDA	J:83346
Cellular Component	GO:0034274	Atg12-Atg5-Atg16 complex	IBA	J:265628
Cellular Component	GO:0005776	autophagosome	ISO	J:92184
Cellular Component	GO:0005776	autophagosome	IDA	J:70539
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0005930	axoneme	IDA	J:203423
Cellular Component	GO:0005737	cytoplasm	IDA	J:70539
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5682677
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-936387
Cellular Component	GO:0016020	membrane	ISO	J:193725
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	IDA	J:195131
Cellular Component	GO:0034045	phagophore assembly site membrane	IDA	J:70539
Cellular Component	GO:0034045	phagophore assembly site membrane	IDA	J:83346
Cellular Component	GO:0034045	phagophore assembly site membrane	IBA	J:265628
Cellular Component	GO:0034045	phagophore assembly site membrane	IDA	J:195131
Cellular Component	GO:0032991	protein-containing complex	NAS	J:319961
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:1990234	transferase complex	IDA	J:164739
Biological Process	GO:0035973	aggrephagy	IMP	J:229367
Biological Process	GO:0035973	aggrephagy	ISO	J:164563
Biological Process	GO:0019883	antigen processing and presentation of endogenous antigen	IGI	J:196474
Biological Process	GO:0019883	antigen processing and presentation of endogenous antigen	IMP	J:196474
Biological Process	GO:0006915	apoptotic process	IMP	J:121778
Biological Process	GO:0000045	autophagosome assembly	IMP	J:70539
Biological Process	GO:0000045	autophagosome assembly	ISO	J:155856
Biological Process	GO:0000045	autophagosome assembly	IBA	J:265628
Biological Process	GO:0000045	autophagosome assembly	IMP	J:199115
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0006914	autophagy	ISO	J:155856
Biological Process	GO:0006914	autophagy	IMP	J:70539
Biological Process	GO:0006914	autophagy	IMP	J:200700
Biological Process	GO:0000422	autophagy of mitochondrion	IMP	J:136548
Biological Process	GO:0000422	autophagy of mitochondrion	IBA	J:265628
Biological Process	GO:0044804	autophagy of nucleus	IBA	J:265628
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:121778
Biological Process	GO:0006501	C-terminal protein lipidation	IBA	J:265628
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	IMP	J:121778
Biological Process	GO:0006995	cellular response to nitrogen starvation	IBA	J:265628
Biological Process	GO:0071500	cellular response to nitrosative stress	IMP	J:200700
Biological Process	GO:0009267	cellular response to starvation	IMP	J:197783
Biological Process	GO:0061684	chaperone-mediated autophagy	ISO	J:155856
Biological Process	GO:0006325	chromatin organization	IMP	J:204746
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:206181
Biological Process	GO:0060047	heart contraction	IMP	J:121778
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0016236	macroautophagy	ISO	J:164563
Biological Process	GO:0016236	macroautophagy	IMP	J:70539
Biological Process	GO:0016236	macroautophagy	IMP	J:197783
Biological Process	GO:0016236	macroautophagy	IMP	J:197783
Biological Process	GO:0016236	macroautophagy	IMP	J:161320
Biological Process	GO:0016236	macroautophagy	IMP	J:208209
Biological Process	GO:0016236	macroautophagy	IMP	J:197783
Biological Process	GO:0016236	macroautophagy	IMP	J:199115
Biological Process	GO:0070254	mucus secretion	IMP	J:206181
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:136548
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1904093	negative regulation of autophagic cell death	ISO	J:73065
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	IMP	J:121778
Biological Process	GO:0050687	negative regulation of defense response to virus	IDA	J:124905
Biological Process	GO:0050687	negative regulation of defense response to virus	ISO	J:164563
Biological Process	GO:0045824	negative regulation of innate immune response	IDA	J:124905
Biological Process	GO:0050765	negative regulation of phagocytosis	IMP	J:208209
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IMP	J:121778
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IMP	J:136548
Biological Process	GO:0032480	negative regulation of type I interferon production	IDA	J:124905
Biological Process	GO:0039689	negative stranded viral RNA replication	IMP	J:206800
Biological Process	GO:0045060	negative thymic T cell selection	IGI	J:196474
Biological Process	GO:0045060	negative thymic T cell selection	IMP	J:196474
Biological Process	GO:0048840	otolith development	IMP	J:163712
Biological Process	GO:0070257	positive regulation of mucus secretion	IMP	J:206181
Biological Process	GO:1904973	positive regulation of viral translation	ISO	J:164563
Biological Process	GO:0043687	post-translational protein modification	IDA	J:70539
Biological Process	GO:0006497	protein lipidation	ISO	J:164563
Biological Process	GO:0061739	protein lipidation involved in autophagosome assembly	IMP	J:205012
Biological Process	GO:0016567	protein ubiquitination	IMP	J:121778
Biological Process	GO:1901096	regulation of autophagosome maturation	ISO	J:164563
Biological Process	GO:1902017	regulation of cilium assembly	IMP	J:203424
Biological Process	GO:1902017	regulation of cilium assembly	IMP	J:203423
Biological Process	GO:0002718	regulation of cytokine production involved in immune response	IMP	J:186989
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	IMP	J:206181
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	IMP	J:206181
Biological Process	GO:0009620	response to fungus	IMP	J:186989
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:121778
Biological Process	GO:0042311	vasodilation	IMP	J:121778
Biological Process	GO:0055015	ventricular cardiac muscle cell development	IMP	J:121778

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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