GO Annotations Graph

• Symbol: Casp9
• Name: caspase 9
• ID: MGI:1277950

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:101402
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	ISO	J:164563
Molecular Function	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	RCA	J:84168
Molecular Function	GO:0008233	peptidase activity	IDA	J:87334
Molecular Function	GO:0008233	peptidase activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:87334
Molecular Function	GO:0005515	protein binding	IPI	J:87334
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Cellular Component	GO:0043293	apoptosome	ISO	J:164563
Cellular Component	GO:0008303	caspase complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6804642
Cellular Component	GO:0005829	cytosol	IDA	J:93333
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:93333
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:97306
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:97306
Biological Process	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IMP	J:105496
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	IDA	J:161020
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:115386
Biological Process	GO:1904019	epithelial cell apoptotic process	IDA	J:130045
Biological Process	GO:0044346	fibroblast apoptotic process	IDA	J:84272
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	NAS	J:320091
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	ISO	J:164563
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IBA	J:265628
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	NAS	J:220516
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:66953
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:66953
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:115386
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:66953
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:115386
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IGI	J:66953
Biological Process	GO:0051604	protein maturation	ISO	J:164563
Biological Process	GO:0016485	protein processing	ISO	J:155856
Biological Process	GO:0006508	proteolysis	RCA	J:84168
Biological Process	GO:0042981	regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0009411	response to UV	IMP	J:115386
Biological Process	GO:0042770	signal transduction in response to DNA damage	ISO	J:164563