GO Annotations Graph

• Symbol: Knstrn
• Name: kinetochore-localized astrin/SPAG5 binding
• ID: MGI:1289298

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051010	microtubule plus-end binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0005815	microtubule organizing center	ISO	J:164563
Cellular Component	GO:0035371	microtubule plus-end	ISO	J:164563
Cellular Component	GO:0035371	microtubule plus-end	IBA	J:265628
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0000070	mitotic sister chromatid segregation	ISO	J:164563
Biological Process	GO:0000070	mitotic sister chromatid segregation	IBA	J:265628
Biological Process	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	IBA	J:265628
Biological Process	GO:0007051	spindle organization	ISO	J:164563
Biological Process	GO:0007051	spindle organization	IBA	J:265628