GO Annotations Graph

• Symbol: Cst7
• Name: cystatin F (leukocystatin)
• ID: MGI:1298217

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	IBA	J:265628
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	IMP	J:242069
Molecular Function	GO:0030414	peptidase inhibitor activity	IDA	J:273526
Molecular Function	GO:0030414	peptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:242069
Cellular Component	GO:0031410	cytoplasmic vesicle	IMP	J:273556
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IMP	J:273556
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:245644
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:273526
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005770	late endosome	IMP	J:273556
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IMP	J:273556
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0005771	multivesicular body	ISO	J:164563
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0097340	inhibition of cysteine-type endopeptidase activity	IBA	J:265628
Biological Process	GO:0097340	inhibition of cysteine-type endopeptidase activity	IMP	J:242069
Biological Process	GO:1903979	negative regulation of microglial cell activation	IBA	J:265628
Biological Process	GO:1903979	negative regulation of microglial cell activation	IMP	J:242069
Biological Process	GO:0010466	negative regulation of peptidase activity	ISO	J:164563
Biological Process	GO:0010466	negative regulation of peptidase activity	IDA	J:273526
Biological Process	GO:0031643	positive regulation of myelination	IBA	J:265628
Biological Process	GO:0031643	positive regulation of myelination	IMP	J:242069