GO Annotations Graph

• Symbol: Sh3pxd2a
• Name: SH3 and PX domains 2A
• ID: MGI:1298393

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	IMP	J:261841
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	IMP	J:261841
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	IMP	J:261841
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IMP	J:261841
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	IMP	J:261841
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	IMP	J:261841
Molecular Function	GO:0002020	protease binding	IPI	J:261841
Molecular Function	GO:0005515	protein binding	IPI	J:175349
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:261841
Cellular Component	GO:0002102	podosome	ISO	J:164563
Cellular Component	GO:0002102	podosome	IDA	J:261841
Biological Process	GO:0001701	in utero embryonic development	IMP	J:240631
Biological Process	GO:0072675	osteoclast fusion	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	IMP	J:175349
Biological Process	GO:0042554	superoxide anion generation	IBA	J:265628
Biological Process	GO:0006801	superoxide metabolic process	ISO	J:164563