GO Annotations Graph

• Symbol: Egr3
• Name: early growth response 3
• ID: MGI:1306780

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:242476
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:241473
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9620402
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0045202	synapse	IMP	J:76256
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ISO	J:164563
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ISO	J:164563
Biological Process	GO:0035767	endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:76256
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:95816
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	IMP	J:174553
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:242476
Biological Process	GO:0045586	regulation of gamma-delta T cell differentiation	IDA	J:174553
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628