GO Annotations Graph

• Symbol: Mapk8ip1
• Name: mitogen-activated protein kinase 8 interacting protein 1
• ID: MGI:1309464

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0008432	JUN kinase binding	ISO	J:155856
Molecular Function	GO:0008432	JUN kinase binding	IBA	J:265628
Molecular Function	GO:0019894	kinesin binding	IPI	J:114032
Molecular Function	GO:0019894	kinesin binding	ISO	J:164563
Molecular Function	GO:0005078	MAP-kinase scaffold activity	NAS	J:77616
Molecular Function	GO:0005078	MAP-kinase scaffold activity	ISO	J:155856
Molecular Function	GO:0005078	MAP-kinase scaffold activity	ISO	J:164563
Molecular Function	GO:0005078	MAP-kinase scaffold activity	IBA	J:265628
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	ISO	J:155856
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:196352
Molecular Function	GO:0005515	protein binding	IPI	J:145809
Molecular Function	GO:0005515	protein binding	IPI	J:113901
Molecular Function	GO:0005515	protein binding	IPI	J:142662
Molecular Function	GO:0005515	protein binding	IPI	J:148055
Molecular Function	GO:0005515	protein binding	IPI	J:205863
Molecular Function	GO:0005515	protein binding	IPI	J:114052
Molecular Function	GO:0019901	protein kinase binding	IPI	J:77616
Cellular Component	GO:0030424	axon	IDA	J:114833
Cellular Component	GO:0030424	axon	IDA	J:114833
Cellular Component	GO:0044295	axonal growth cone	ISO	J:114833
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:114833
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:114833
Cellular Component	GO:0030425	dendrite	IDA	J:114833
Cellular Component	GO:0044294	dendritic growth cone	ISO	J:114833
Cellular Component	GO:0044302	dentate gyrus mossy fiber	IDA	J:114833
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0016020	membrane	IDA	J:114833
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IDA	J:104505
Cellular Component	GO:0043025	neuronal cell body	IDA	J:114833
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	IDA	J:114833
Cellular Component	GO:0045202	synapse	IDA	J:114833
Cellular Component	GO:0045202	synapse	IDA	J:114833
Cellular Component	GO:0045202	synapse	IDA	J:114833
Cellular Component	GO:0045202	synapse	IDA	J:114833
Biological Process	GO:0007254	JNK cascade	IBA	J:265628
Biological Process	GO:0007258	JUN phosphorylation	IDA	J:50502
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	IDA	J:53500
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0043508	negative regulation of JUN kinase activity	ISO	J:155856
Biological Process	GO:0046330	positive regulation of JNK cascade	IMP	J:205863
Biological Process	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation	IMP	J:205863
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:50502
Biological Process	GO:0046328	regulation of JNK cascade	IMP	J:77616
Biological Process	GO:0007165	signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IDA	J:50502
Biological Process	GO:0016192	vesicle-mediated transport	IDA	J:104505