GO Annotations Graph

• Symbol: Casq1
• Name: calsequestrin 1
• ID: MGI:1309468

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IDA	J:212821
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0031674	I band	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:212821
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0030016	myofibril	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:212821
Cellular Component	GO:0016529	sarcoplasmic reticulum	TAS	J:72636
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:88884
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:81492
Cellular Component	GO:0033018	sarcoplasmic reticulum lumen	IDA	J:180615
Cellular Component	GO:0033018	sarcoplasmic reticulum lumen	IBA	J:265628
Cellular Component	GO:0033018	sarcoplasmic reticulum lumen	IDA	J:108863
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:0014802	terminal cisterna	ISO	J:155856
Cellular Component	GO:0014804	terminal cisterna lumen	ISO	J:155856
Biological Process	GO:0007029	endoplasmic reticulum organization	IMP	J:140828
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:1901341	positive regulation of store-operated calcium channel activity	ISO	J:164563
Biological Process	GO:0051258	protein polymerization	ISO	J:164563
Biological Process	GO:0006937	regulation of muscle contraction	TAS	J:72636
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IDA	J:81492
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IMP	J:140828
Biological Process	GO:0051282	regulation of sequestering of calcium ion	ISO	J:155856
Biological Process	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	IMP	J:180615
Biological Process	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	IBA	J:265628
Biological Process	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	IMP	J:140828
Biological Process	GO:2001256	regulation of store-operated calcium entry	ISO	J:164563
Biological Process	GO:0009408	response to heat	IMP	J:150541
Biological Process	GO:0045214	sarcomere organization	IMP	J:180615