GO Annotations Graph

• Symbol: Ppp1r12a
• Name: protein phosphatase 1, regulatory subunit 12A
• ID: MGI:1309528

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0004857	enzyme inhibitor activity	ISO	J:164563
Molecular Function	GO:0004857	enzyme inhibitor activity	IBA	J:265628
Molecular Function	GO:0019208	phosphatase regulator activity	ISO	J:164563
Molecular Function	GO:0019208	phosphatase regulator activity	IBA	J:265628
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:166394
Molecular Function	GO:0005515	protein binding	IPI	J:134634
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Cellular Component	GO:0031672	A band	IDA	J:224746
Cellular Component	GO:0031672	A band	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0043292	contractile fiber	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0072357	PTW/PP1 phosphatase complex	ISO	J:164563
Cellular Component	GO:0030018	Z disc	IDA	J:224746
Cellular Component	GO:0030018	Z disc	IBA	J:265628
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:138635
Biological Process	GO:0007098	centrosome cycle	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	ISO	J:164563
Biological Process	GO:0043086	negative regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0035508	positive regulation of myosin-light-chain-phosphatase activity	ISO	J:164563
Biological Process	GO:0035508	positive regulation of myosin-light-chain-phosphatase activity	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:119479
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0035507	regulation of myosin-light-chain-phosphatase activity	ISO	J:164563
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	IMP	J:119479
Biological Process	GO:0007165	signal transduction	IEA	J:72247