GO Annotations Graph

• Symbol: Slfn1
• Name: schlafen 1
• ID: MGI:1313259

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140102	catalytic activity, acting on a rRNA	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:138087
Molecular Function	GO:0043022	ribosome binding	ISO	J:164563
Molecular Function	GO:0004540	RNA nuclease activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:138087
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:138087
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:51308
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IGI	J:101034
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IDA	J:51308
Biological Process	GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	IDA	J:101034
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IDA	J:101034
Biological Process	GO:0042130	negative regulation of T cell proliferation	IDA	J:138087
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:138087
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:51308
Biological Process	GO:0042098	T cell proliferation	IDA	J:138087