Vamp2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vamp2
vesicle-associated membrane protein 2
MGI:1313277

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IDA	J:78421
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0008289	lipid binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0017022	myosin binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	IDA	J:78421
Molecular Function	GO:0005515	protein binding	IPI	J:266473
Molecular Function	GO:0005515	protein binding	IPI	J:218865
Molecular Function	GO:0005515	protein binding	IPI	J:119733
Molecular Function	GO:0005515	protein binding	IPI	J:157635
Molecular Function	GO:0005515	protein binding	IPI	J:159065
Molecular Function	GO:0005515	protein binding	IPI	J:245395
Molecular Function	GO:0005515	protein binding	IPI	J:273533
Molecular Function	GO:0005515	protein binding	IPI	J:140958
Molecular Function	GO:0005515	protein binding	IPI	J:248215
Molecular Function	GO:0005515	protein binding	IPI	J:181971
Molecular Function	GO:0005515	protein binding	IPI	J:157584
Molecular Function	GO:0005515	protein binding	IPI	J:200387
Molecular Function	GO:0005515	protein binding	IPI	J:225407
Molecular Function	GO:0005515	protein binding	IPI	J:164218
Molecular Function	GO:0005515	protein binding	IPI	J:167753
Molecular Function	GO:0005515	protein binding	IPI	J:55848
Molecular Function	GO:0005515	protein binding	IPI	J:140969
Molecular Function	GO:0005515	protein binding	IPI	J:151132
Molecular Function	GO:0005515	protein binding	IPI	J:167753
Molecular Function	GO:0005515	protein binding	IPI	J:167753
Molecular Function	GO:0005515	protein binding	IPI	J:139769
Molecular Function	GO:0005515	protein binding	IPI	J:167753
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005484	SNAP receptor activity	IBA	J:265628
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	IDA	J:78421
Molecular Function	GO:0000149	SNARE binding	ISO	J:29256
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Molecular Function	GO:0019905	syntaxin binding	IPI	J:161112
Molecular Function	GO:0017075	syntaxin-1 binding	IDA	J:138035
Molecular Function	GO:0017075	syntaxin-1 binding	ISO	J:155856
Molecular Function	GO:0017075	syntaxin-1 binding	IBA	J:265628
Molecular Function	GO:0017075	syntaxin-1 binding	ISO	J:29256
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:164563
Cellular Component	GO:0060203	clathrin-sculpted glutamate transport vesicle membrane	TAS	Reactome:R-MMU-9664156
Cellular Component	GO:0005737	cytoplasm	IDA	J:273533
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:139769
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	TAS	Reactome:R-MMU-1449573
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IDA	J:80816
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043229	intracellular organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:197701
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0044306	neuron projection terminus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:140958
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:139769
Cellular Component	GO:0005886	plasma membrane	IDA	J:182176
Cellular Component	GO:0030141	secretory granule	IDA	J:273533
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Cellular Component	GO:0030141	secretory granule	IDA	J:78421
Cellular Component	GO:0030667	secretory granule membrane	TAS	Reactome:R-MMU-216883
Cellular Component	GO:0031201	SNARE complex	ISO	J:164563
Cellular Component	GO:0031201	SNARE complex	ISO	J:155856
Cellular Component	GO:0031201	SNARE complex	IBA	J:265628
Cellular Component	GO:0031201	SNARE complex	IDA	J:137704
Cellular Component	GO:0000322	storage vacuole	IDA	J:182176
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:167591
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:213593
Cellular Component	GO:0045202	synapse	IDA	J:140969
Cellular Component	GO:0045202	synapse	IDA	J:201692
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:91381
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:84542
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:90137
Cellular Component	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	ISO	J:155856
Cellular Component	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	ISO	J:29256
Cellular Component	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	IDA	J:167753
Cellular Component	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	ISO	J:29256
Cellular Component	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:140958
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Cellular Component	GO:0031982	vesicle	IDA	J:225407
Cellular Component	GO:0042589	zymogen granule membrane	IDA	J:84542
Biological Process	GO:0017156	calcium-ion regulated exocytosis	IMP	J:100913
Biological Process	GO:0017156	calcium-ion regulated exocytosis	IDA	J:78421
Biological Process	GO:0032869	cellular response to insulin stimulus	IDA	J:131844
Biological Process	GO:0043308	eosinophil degranulation	ISO	J:164563
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:100913
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	IMP	J:197846
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	ISO	J:155856
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	IMP	J:165162
Biological Process	GO:0046879	hormone secretion	IDA	J:273533
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:197846
Biological Process	GO:0061025	membrane fusion	IMP	J:100913
Biological Process	GO:0090316	positive regulation of intracellular protein transport	IMP	J:131844
Biological Process	GO:0015031	protein transport	ISO	J:155856
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0045055	regulated exocytosis	IDA	J:273533
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	TAS	J:212808
Biological Process	GO:1902259	regulation of delayed rectifier potassium channel activity	ISO	J:155856
Biological Process	GO:0017157	regulation of exocytosis	ISO	J:155856
Biological Process	GO:0017157	regulation of exocytosis	IDA	J:78421
Biological Process	GO:1903421	regulation of synaptic vesicle recycling	ISO	J:155856
Biological Process	GO:0060627	regulation of vesicle-mediated transport	IMP	J:131844
Biological Process	GO:0009749	response to glucose	ISO	J:155856
Biological Process	GO:0035493	SNARE complex assembly	ISO	J:155856
Biological Process	GO:0035493	SNARE complex assembly	IBA	J:265628
Biological Process	GO:0016081	synaptic vesicle docking	IDA	J:218225
Biological Process	GO:0016081	synaptic vesicle docking	IMP	J:218225
Biological Process	GO:0016081	synaptic vesicle docking	IDA	J:218225
Biological Process	GO:0016081	synaptic vesicle docking	IDA	J:218225
Biological Process	GO:0048488	synaptic vesicle endocytosis	IMP	J:96873
Biological Process	GO:0016079	synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0016079	synaptic vesicle exocytosis	IMP	J:96873
Biological Process	GO:0016079	synaptic vesicle exocytosis	IMP	J:72714
Biological Process	GO:0006906	vesicle fusion	ISO	J:164563
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628
Biological Process	GO:0016192	vesicle-mediated transport	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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