GO Annotations Graph

• Symbol: Tnfrsf1b
• Name: tumor necrosis factor receptor superfamily, member 1b
• ID: MGI:1314883

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:121814
Molecular Function	GO:0005515	protein binding	IPI	J:121814
Molecular Function	GO:0043120	tumor necrosis factor binding	ISO	J:164563
Molecular Function	GO:0043120	tumor necrosis factor binding	IBA	J:265628
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	ISO	J:155856
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	IBA	J:265628
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	IPI	J:11207
Molecular Function	GO:0005031	tumor necrosis factor receptor activity	IPI	J:11207
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:121814
Cellular Component	GO:0045121	membrane raft	IDA	J:143672
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0043196	varicosity	ISO	J:155856
Biological Process	GO:0003176	aortic valve development	IGI	J:261826
Biological Process	GO:0007166	cell surface receptor signaling pathway	IMP	J:45147
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IMP	J:21815
Biological Process	GO:0150098	glial cell-neuron signaling	IMP	J:231813
Biological Process	GO:0006955	immune response	ISO	J:155856
Biological Process	GO:0006954	inflammatory response	IMP	J:45147
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IBA	J:265628
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:121372
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	IGI	J:261826
Biological Process	GO:0060548	negative regulation of cell death	IMP	J:231813
Biological Process	GO:0003332	negative regulation of extracellular matrix constituent secretion	IGI	J:261826
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:72219
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	IMP	J:231813
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	IBA	J:265628
Biological Process	GO:1901215	negative regulation of neuron death	IMP	J:231813
Biological Process	GO:1901215	negative regulation of neuron death	IBA	J:265628
Biological Process	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	IGI	J:261826
Biological Process	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	IGI	J:261826
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	ISO	J:164563
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	IBA	J:265628
Biological Process	GO:0031643	positive regulation of myelination	IMP	J:231813
Biological Process	GO:0031643	positive regulation of myelination	IBA	J:265628
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	IMP	J:231813
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	IBA	J:265628
Biological Process	GO:0003177	pulmonary valve development	IGI	J:261826
Biological Process	GO:0002718	regulation of cytokine production involved in immune response	IGI	J:240627
Biological Process	GO:0031641	regulation of myelination	IGI	J:240627
Biological Process	GO:0150077	regulation of neuroinflammatory response	IGI	J:240627
Biological Process	GO:2001141	regulation of RNA biosynthetic process	IMP	J:231813
Biological Process	GO:0002724	regulation of T cell cytokine production	IMP	J:240627
Biological Process	GO:0002724	regulation of T cell cytokine production	IBA	J:265628
Biological Process	GO:0042129	regulation of T cell proliferation	IMP	J:240627
Biological Process	GO:0042129	regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0050779	RNA destabilization	IMP	J:72219