GO Annotations Graph

• Symbol: Prmt2
• Name: protein arginine N-methyltransferase 2
• ID: MGI:1316652

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:190282
Molecular Function	GO:0140938	histone H3 methyltransferase activity	IDA	J:190282
Molecular Function	GO:0042054	histone methyltransferase activity	ISO	J:164563
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:72247
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0050681	nuclear androgen receptor binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:164563
Molecular Function	GO:0033142	nuclear progesterone receptor binding	ISO	J:164563
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:164563
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:164563
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:111352
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	IMP	J:178194
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	IEA	J:72245
Molecular Function	GO:0044877	protein-containing complex binding	IPI	J:111352
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0048588	developmental cell growth	IMP	J:178194
Biological Process	GO:0033210	leptin-mediated signaling pathway	NAS	J:178194
Biological Process	GO:0032259	methylation	NAS	J:178194
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	IMP	J:111352
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:111352
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IMP	J:111352
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0018216	peptidyl-arginine methylation	IEA	J:72247
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	NAS	J:178194
Biological Process	GO:0001666	response to hypoxia	IDA	J:126896