Men1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Men1
multiple endocrine neoplasia 1
MGI:1316736

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:96252
Molecular Function	GO:0003682	chromatin binding	IDA	J:105708
Molecular Function	GO:0003682	chromatin binding	IDA	J:102494
Molecular Function	GO:0003682	chromatin binding	IDA	J:96252
Molecular Function	GO:0003682	chromatin binding	IDA	J:102494
Molecular Function	GO:0003677	DNA binding	IDA	J:215255
Molecular Function	GO:0003677	DNA binding	IDA	J:88588
Molecular Function	GO:0001216	DNA-binding transcription activator activity	IDA	J:88588
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000400	four-way junction DNA binding	ISO	J:164563
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:226000
Molecular Function	GO:0005515	protein binding	IPI	J:177497
Molecular Function	GO:0005515	protein binding	IPI	J:93345
Molecular Function	GO:0005515	protein binding	IPI	J:93345
Molecular Function	GO:0005515	protein binding	IPI	J:93345
Molecular Function	GO:0005515	protein binding	IPI	J:93345
Molecular Function	GO:0005515	protein binding	IPI	J:109102
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0070412	R-SMAD binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:165919
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:88588
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Molecular Function	GO:0000403	Y-form DNA binding	ISO	J:164563
Molecular Function	GO:0000403	Y-form DNA binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:229375
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:51201
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	IBA	J:265628
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:88588
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0044665	MLL1/2 complex	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:116086
Cellular Component	GO:0005634	nucleus	IDA	J:51201
Cellular Component	GO:0005634	nucleus	IDA	J:93345
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Cellular Component	GO:0005634	nucleus	IDA	J:85133
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:102494
Cellular Component	GO:0005634	nucleus	IDA	J:51201
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0051301	cell division	IMP	J:102494
Biological Process	GO:0051301	cell division	IMP	J:110111
Biological Process	GO:0051301	cell division	IMP	J:102494
Biological Process	GO:0008283	cell population proliferation	IMP	J:86642
Biological Process	GO:0008283	cell population proliferation	IMP	J:127545
Biological Process	GO:0008283	cell population proliferation	IGI	J:120835
Biological Process	GO:0008283	cell population proliferation	IMP	J:89898
Biological Process	GO:0008283	cell population proliferation	IMP	J:85133
Biological Process	GO:0008283	cell population proliferation	IMP	J:110111
Biological Process	GO:0008283	cell population proliferation	IMP	J:102494
Biological Process	GO:0008283	cell population proliferation	IDA	J:127140
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IMP	J:105625
Biological Process	GO:0006338	chromatin remodeling	IGI	J:105708
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0009790	embryo development	IMP	J:67128
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:127545
Biological Process	GO:0044346	fibroblast apoptotic process	IGI	J:88866
Biological Process	GO:0044346	fibroblast apoptotic process	IDA	J:88866
Biological Process	GO:0044346	fibroblast apoptotic process	IGI	J:88866
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:110111
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:96252
Biological Process	GO:0030097	hemopoiesis	IMP	J:105708
Biological Process	GO:0001776	leukocyte homeostasis	IMP	J:105708
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0060135	maternal process involved in female pregnancy	IDA	J:127140
Biological Process	GO:0045786	negative regulation of cell cycle	ISO	J:164563
Biological Process	GO:0045786	negative regulation of cell cycle	IBA	J:265628
Biological Process	GO:1902807	negative regulation of cell cycle G1/S phase transition	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:86642
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:67128
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:105625
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:110111
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:110111
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:96252
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0046621	negative regulation of organ growth	IDA	J:127140
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	ISO	J:73065
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IDA	J:93345
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IGI	J:96882
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IGI	J:120835
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IMP	J:127545
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:105625
Biological Process	GO:1904691	negative regulation of type B pancreatic cell proliferation	IMP	J:102494
Biological Process	GO:1904691	negative regulation of type B pancreatic cell proliferation	IDA	J:127140
Biological Process	GO:1904691	negative regulation of type B pancreatic cell proliferation	IMP	J:85133
Biological Process	GO:1904691	negative regulation of type B pancreatic cell proliferation	IMP	J:89898
Biological Process	GO:0035265	organ growth	IDA	J:127140
Biological Process	GO:0001503	ossification	IMP	J:127545
Biological Process	GO:0002076	osteoblast development	IGI	J:96882
Biological Process	GO:0002076	osteoblast development	ISO	J:73065
Biological Process	GO:0002076	osteoblast development	IGI	J:93345
Biological Process	GO:0002051	osteoblast fate commitment	IGI	J:93345
Biological Process	GO:0002051	osteoblast fate commitment	IGI	J:93345
Biological Process	GO:0002051	osteoblast fate commitment	IGI	J:93345
Biological Process	GO:0051781	positive regulation of cell division	IMP	J:110111
Biological Process	GO:0051781	positive regulation of cell division	IMP	J:102494
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:88866
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:88588
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IDA	J:88866
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IGI	J:88866
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IGI	J:88866
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215255
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:102494
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:88588
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:102494
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:105708
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:215255
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IGI	J:93345
Biological Process	GO:2000738	positive regulation of stem cell differentiation	IMP	J:127545
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:165919
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:105708
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:102494
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:93345
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:93345
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:102494
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:96252
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0032925	regulation of activin receptor signaling pathway	ISO	J:155856
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:110111
Biological Process	GO:0010468	regulation of gene expression	IDA	J:215255
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	ISO	J:155856
Biological Process	GO:0010332	response to gamma radiation	ISO	J:164563
Biological Process	GO:0071559	response to transforming growth factor beta	ISO	J:155856
Biological Process	GO:0009411	response to UV	ISO	J:164563
Biological Process	GO:0060021	roof of mouth development	IMP	J:127545
Biological Process	GO:0048863	stem cell differentiation	IMP	J:127545
Biological Process	GO:0072089	stem cell proliferation	IMP	J:127545
Biological Process	GO:0072089	stem cell proliferation	IGI	J:120835
Biological Process	GO:0045064	T-helper 2 cell differentiation	ISO	J:164563
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	IMP	J:88588
Biological Process	GO:0003309	type B pancreatic cell differentiation	ISO	J:155856
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:85133
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:102494
Biological Process	GO:0044342	type B pancreatic cell proliferation	IDA	J:127140
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:89898

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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