GO Annotations Graph

• Symbol: Ptprt
• Name: protein tyrosine phosphatase receptor type T
• ID: MGI:1321152

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051393	alpha-actinin binding	IDA	J:114547
Molecular Function	GO:0045294	alpha-catenin binding	ISO	J:164563
Molecular Function	GO:0045294	alpha-catenin binding	IDA	J:114547
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0008013	beta-catenin binding	IDA	J:114547
Molecular Function	GO:0045296	cadherin binding	ISO	J:164563
Molecular Function	GO:0045296	cadherin binding	IPI	J:114547
Molecular Function	GO:0045296	cadherin binding	IPI	J:114547
Molecular Function	GO:0045296	cadherin binding	IPI	J:114547
Molecular Function	GO:0070097	delta-catenin binding	ISO	J:164563
Molecular Function	GO:0070097	delta-catenin binding	IPI	J:114547
Molecular Function	GO:0045295	gamma-catenin binding	ISO	J:164563
Molecular Function	GO:0045295	gamma-catenin binding	IPI	J:114547
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	TAS	Reactome:R-NUL-420388
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IMP	J:114547
Molecular Function	GO:0097677	STAT family protein binding	ISO	J:164563
Molecular Function	GO:0016790	thiolester hydrolase activity	IDA	J:114547
Molecular Function	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-420388
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-420398
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Biological Process	GO:0071354	cellular response to interleukin-6	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:1904893	negative regulation of receptor signaling pathway via STAT	ISO	J:164563
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:164563
Biological Process	GO:1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:114547
Biological Process	GO:0050807	regulation of synapse organization	ISO	J:155856
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	ISO	J:164563