GO Annotations Graph

• Symbol: Ppp2cb
• Name: protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
• ID: MGI:1321161

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:116445
Molecular Function	GO:0005515	protein binding	IPI	J:84681
Molecular Function	GO:0005515	protein binding	IPI	J:84681
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	ISO	J:155856
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:62090
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-209096
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	TAS	J:62090
Cellular Component	GO:0000159	protein phosphatase type 2A complex	IDA	J:116445
Biological Process	GO:0008637	apoptotic mitochondrial changes	IMP	J:116445
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	ISO	J:164563
Biological Process	GO:1904528	positive regulation of microtubule binding	ISO	J:155856
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	J:116445
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:155856
Biological Process	GO:0010468	regulation of gene expression	IMP	J:116445
Biological Process	GO:0046677	response to antibiotic	IMP	J:116445
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:116445
Biological Process	GO:0042542	response to hydrogen peroxide	IMP	J:116445
Biological Process	GO:0010288	response to lead ion	ISO	J:155856