GO Annotations Graph

• Symbol: Enpp2
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
• ID: MGI:1321390

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity	ISO	J:155856
Molecular Function	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity	IBA	J:265628
Molecular Function	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity	IDA	J:91157
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IDA	J:173719
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0004551	dinucleotide phosphatase activity	ISS	J:56413
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004622	lysophospholipase activity	ISO	J:164563
Molecular Function	GO:0004622	lysophospholipase activity	ISO	J:155856
Molecular Function	GO:0004622	lysophospholipase activity	IDA	J:173719
Molecular Function	GO:0004622	lysophospholipase activity	IBA	J:265628
Molecular Function	GO:0004622	lysophospholipase activity	IDA	J:234535
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0004528	phosphodiesterase I activity	ISO	J:155856
Molecular Function	GO:0004528	phosphodiesterase I activity	IBA	J:265628
Molecular Function	GO:0004528	phosphodiesterase I activity	ISS	J:56413
Molecular Function	GO:0030247	polysaccharide binding	IEA	J:72247
Molecular Function	GO:0005044	scavenger receptor activity	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	IDA	J:173719
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:173719
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISS	J:56413
Biological Process	GO:0060326	cell chemotaxis	ISO	J:155856
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0006935	chemotaxis	IEA	J:72247
Biological Process	GO:0044849	estrous cycle	IBA	J:265628
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	ISO	J:155856
Biological Process	GO:0034638	phosphatidylcholine catabolic process	ISO	J:155856
Biological Process	GO:0034638	phosphatidylcholine catabolic process	IDA	J:173719
Biological Process	GO:0034638	phosphatidylcholine catabolic process	ISO	J:164563
Biological Process	GO:0034638	phosphatidylcholine catabolic process	IBA	J:265628
Biological Process	GO:0009395	phospholipid catabolic process	ISO	J:164563
Biological Process	GO:0006644	phospholipid metabolic process	IDA	J:234535
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	ISO	J:155856
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	ISO	J:155856
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:155856
Biological Process	GO:0045765	regulation of angiogenesis	IEA	J:72247
Biological Process	GO:0030334	regulation of cell migration	ISO	J:164563
Biological Process	GO:0030149	sphingolipid catabolic process	ISO	J:164563