GO Annotations Graph

• Symbol: Timeless
• Name: timeless circadian clock 1
• ID: MGI:1321393

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:84659
Molecular Function	GO:0005515	protein binding	IPI	J:209425
Molecular Function	GO:0005515	protein binding	IPI	J:51392
Molecular Function	GO:0005515	protein binding	IPI	J:212062
Molecular Function	GO:0005515	protein binding	IPI	J:84659
Molecular Function	GO:0005515	protein binding	IPI	J:57184
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:209425
Cellular Component	GO:0005634	nucleus	IDA	J:212062
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:85486
Cellular Component	GO:0005634	nucleus	IDA	J:84659
Cellular Component	GO:0005634	nucleus	IDA	J:85486
Cellular Component	GO:0031298	replication fork protection complex	IBA	J:265628
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	ISO	J:155856
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	ISO	J:73065
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IMP	J:85486
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0044770	cell cycle phase transition	ISO	J:164563
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:1904976	cellular response to bleomycin	ISO	J:164563
Biological Process	GO:0072719	cellular response to cisplatin	ISO	J:164563
Biological Process	GO:0072711	cellular response to hydroxyurea	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IEP	J:212062
Biological Process	GO:0007623	circadian rhythm	IEP	J:57184
Biological Process	GO:0006974	DNA damage response	IMP	J:212062
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IBA	J:265628
Biological Process	GO:0000076	DNA replication checkpoint signaling	IBA	J:265628
Biological Process	GO:0009790	embryo development	IMP	J:63669
Biological Process	GO:0001822	kidney development	ISO	J:155856
Biological Process	GO:0030324	lung development	IMP	J:85486
Biological Process	GO:0002009	morphogenesis of an epithelium	IEP	J:64379
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TAS	J:52985
Biological Process	GO:0042753	positive regulation of circadian rhythm	ISO	J:155856
Biological Process	GO:2000781	positive regulation of double-strand break repair	ISO	J:164563
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:212062
Biological Process	GO:0042752	regulation of circadian rhythm	ISO	J:164563
Biological Process	GO:0043111	replication fork arrest	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000