Symbol Name ID |
Trex1
three prime repair exonuclease 1 MGI:1328317 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0008408 | 3'-5' exonuclease activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0008408 | 3'-5' exonuclease activity | IMP | J:92264 | |||||||||
Molecular Function | GO:0008296 | 3'-5'-DNA exonuclease activity | IDA | J:197521 | |||||||||
Molecular Function | GO:0008296 | 3'-5'-DNA exonuclease activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0008296 | 3'-5'-DNA exonuclease activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0032558 | adenyl deoxyribonucleotide binding | IDA | J:121158 | |||||||||
Molecular Function | GO:0003677 | DNA binding | IDA | J:166550 | |||||||||
Molecular Function | GO:0008301 | DNA binding, bending | IDA | J:220965 | |||||||||
Molecular Function | GO:0008311 | double-stranded DNA 3'-5' DNA exonuclease activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0003690 | double-stranded DNA binding | IDA | J:220965 | |||||||||
Molecular Function | GO:0003690 | double-stranded DNA binding | IDA | J:145965 | |||||||||
Molecular Function | GO:0004527 | exonuclease activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0016787 | hydrolase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | IPI | J:121158 | |||||||||
Molecular Function | GO:0000287 | magnesium ion binding | IDA | J:220965 | |||||||||
Molecular Function | GO:0046872 | metal ion binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0140678 | molecular function inhibitor activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0032405 | MutLalpha complex binding | ISO | J:111285 | |||||||||
Molecular Function | GO:0032407 | MutSalpha complex binding | ISO | J:111285 | |||||||||
Molecular Function | GO:0004518 | nuclease activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0003676 | nucleic acid binding | IEA | J:72247 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:197521 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:197521 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:145466 | |||||||||
Molecular Function | GO:0042803 | protein homodimerization activity | IPI | J:197521 | |||||||||
Molecular Function | GO:0003697 | single-stranded DNA binding | IDA | J:122553 | |||||||||
Molecular Function | GO:0003697 | single-stranded DNA binding | IDA | J:121158 | |||||||||
Molecular Function | GO:0050699 | WW domain binding | IDA | J:122553 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | IBA | J:265628 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | IDA | J:173423 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | IDA | J:122553 | |||||||||
Cellular Component | GO:0005829 | cytosol | ISO | J:164563 | |||||||||
Cellular Component | GO:0005829 | cytosol | IDA | J:243357 | |||||||||
Cellular Component | GO:0005783 | endoplasmic reticulum | IDA | J:233654 | |||||||||
Cellular Component | GO:0005783 | endoplasmic reticulum | IDA | J:145466 | |||||||||
Cellular Component | GO:0005789 | endoplasmic reticulum membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0016020 | membrane | IEA | J:60000 | |||||||||
Cellular Component | GO:0043596 | nuclear replication fork | IDA | J:141548 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:173423 | |||||||||
Cellular Component | GO:0005634 | nucleus | IDA | J:141548 | |||||||||
Cellular Component | GO:0008250 | oligosaccharyltransferase complex | IDA | J:233654 | |||||||||
Cellular Component | GO:0032993 | protein-DNA complex | IDA | J:220965 | |||||||||
Biological Process | GO:0002253 | activation of immune response | IMP | J:141548 | |||||||||
Biological Process | GO:0002250 | adaptive immune response | IMP | J:220965 | |||||||||
Biological Process | GO:0043277 | apoptotic cell clearance | IMP | J:207137 | |||||||||
Biological Process | GO:0003228 | atrial cardiac muscle tissue development | IMP | J:92264 | |||||||||
Biological Process | GO:0001568 | blood vessel development | IMP | J:220965 | |||||||||
Biological Process | GO:0035781 | CD86 biosynthetic process | IMP | J:207137 | |||||||||
Biological Process | GO:0071480 | cellular response to gamma radiation | IMP | J:141548 | |||||||||
Biological Process | GO:0072711 | cellular response to hydroxyurea | IMP | J:141548 | |||||||||
Biological Process | GO:0035458 | cellular response to interferon-beta | IDA | J:145965 | |||||||||
Biological Process | GO:0071310 | cellular response to organic substance | IMP | J:243357 | |||||||||
Biological Process | GO:0034599 | cellular response to oxidative stress | IMP | J:208222 | |||||||||
Biological Process | GO:0034614 | cellular response to reactive oxygen species | IMP | J:208222 | |||||||||
Biological Process | GO:0071357 | cellular response to type I interferon | IMP | J:251493 | |||||||||
Biological Process | GO:0034644 | cellular response to UV | IDA | J:173423 | |||||||||
Biological Process | GO:0051607 | defense response to virus | IMP | J:191073 | |||||||||
Biological Process | GO:0051607 | defense response to virus | IMP | J:166550 | |||||||||
Biological Process | GO:0008340 | determination of adult lifespan | IGI | J:239522 | |||||||||
Biological Process | GO:0008340 | determination of adult lifespan | IMP | J:92264 | |||||||||
Biological Process | GO:0008340 | determination of adult lifespan | IGI | J:226998 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IBA | J:265628 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IMP | J:155554 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IMP | J:220965 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IDA | J:166550 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IMP | J:145466 | |||||||||
Biological Process | GO:0006308 | DNA catabolic process | IMP | J:208222 | |||||||||
Biological Process | GO:0000077 | DNA damage checkpoint signaling | IMP | J:141548 | |||||||||
Biological Process | GO:0006974 | DNA damage response | IDA | J:173423 | |||||||||
Biological Process | GO:0032508 | DNA duplex unwinding | IDA | J:220965 | |||||||||
Biological Process | GO:0006259 | DNA metabolic process | IDA | J:197521 | |||||||||
Biological Process | GO:0006304 | DNA modification | IMP | J:209222 | |||||||||
Biological Process | GO:0006260 | DNA replication | IMP | J:173423 | |||||||||
Biological Process | GO:1904161 | DNA synthesis involved in UV-damage excision repair | IMP | J:208222 | |||||||||
Biological Process | GO:0045184 | establishment of protein localization | IMP | J:191073 | |||||||||
Biological Process | GO:0051319 | G2 phase | IMP | J:141548 | |||||||||
Biological Process | GO:0006091 | generation of precursor metabolites and energy | IMP | J:239522 | |||||||||
Biological Process | GO:0003007 | heart morphogenesis | IMP | J:92264 | |||||||||
Biological Process | GO:0003015 | heart process | IMP | J:92264 | |||||||||
Biological Process | GO:0097281 | immune complex formation | IMP | J:220965 | |||||||||
Biological Process | GO:0006955 | immune response | IMP | J:251493 | |||||||||
Biological Process | GO:0002383 | immune response in brain or nervous system | IMP | J:207137 | |||||||||
Biological Process | GO:0002381 | immunoglobulin production involved in immunoglobulin-mediated immune response | IMP | J:220965 | |||||||||
Biological Process | GO:0006954 | inflammatory response | IMP | J:243357 | |||||||||
Biological Process | GO:0006954 | inflammatory response | IMP | J:220965 | |||||||||
Biological Process | GO:0006954 | inflammatory response | IMP | J:92264 | |||||||||
Biological Process | GO:0002437 | inflammatory response to antigenic stimulus | IMP | J:207137 | |||||||||
Biological Process | GO:0045087 | innate immune response | IMP | J:191073 | |||||||||
Biological Process | GO:0032607 | interferon-alpha production | IMP | J:207137 | |||||||||
Biological Process | GO:0001822 | kidney development | IMP | J:220965 | |||||||||
Biological Process | GO:0002320 | lymphoid progenitor cell differentiation | IMP | J:220965 | |||||||||
Biological Process | GO:0002281 | macrophage activation involved in immune response | IMP | J:207137 | |||||||||
Biological Process | GO:0031571 | mitotic G1 DNA damage checkpoint signaling | IMP | J:141548 | |||||||||
Biological Process | GO:0031571 | mitotic G1 DNA damage checkpoint signaling | IMP | J:208222 | |||||||||
Biological Process | GO:0045824 | negative regulation of innate immune response | ISO | J:164563 | |||||||||
Biological Process | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway | IMP | J:145466 | |||||||||
Biological Process | GO:0002251 | organ or tissue specific immune response | IMP | J:207137 | |||||||||
Biological Process | GO:0050821 | protein stabilization | IDA | J:233654 | |||||||||
Biological Process | GO:0050790 | regulation of catalytic activity | IMP | J:191073 | |||||||||
Biological Process | GO:0031323 | regulation of cellular metabolic process | IGI | J:239522 | |||||||||
Biological Process | GO:0031323 | regulation of cellular metabolic process | IMP | J:239522 | |||||||||
Biological Process | GO:0031323 | regulation of cellular metabolic process | IGI | J:239522 | |||||||||
Biological Process | GO:0043457 | regulation of cellular respiration | IMP | J:239522 | |||||||||
Biological Process | GO:0019217 | regulation of fatty acid metabolic process | IMP | J:239522 | |||||||||
Biological Process | GO:0010468 | regulation of gene expression | IGI | J:191073 | |||||||||
Biological Process | GO:0010468 | regulation of gene expression | IGI | J:191073 | |||||||||
Biological Process | GO:0010468 | regulation of gene expression | IMP | J:191073 | |||||||||
Biological Process | GO:0010468 | regulation of gene expression | IGI | J:191073 | |||||||||
Biological Process | GO:0010468 | regulation of gene expression | IGI | J:191073 | |||||||||
Biological Process | GO:0006110 | regulation of glycolytic process | IMP | J:239522 | |||||||||
Biological Process | GO:0002637 | regulation of immunoglobulin production | IMP | J:233654 | |||||||||
Biological Process | GO:0002637 | regulation of immunoglobulin production | IGI | J:226998 | |||||||||
Biological Process | GO:0050727 | regulation of inflammatory response | IGI | J:239522 | |||||||||
Biological Process | GO:0050727 | regulation of inflammatory response | IGI | J:239522 | |||||||||
Biological Process | GO:0045088 | regulation of innate immune response | IMP | J:233654 | |||||||||
Biological Process | GO:0045088 | regulation of innate immune response | IMP | J:166550 | |||||||||
Biological Process | GO:0046890 | regulation of lipid biosynthetic process | IGI | J:239522 | |||||||||
Biological Process | GO:1905671 | regulation of lysosome organization | IMP | J:191073 | |||||||||
Biological Process | GO:0061635 | regulation of protein complex stability | IMP | J:233654 | |||||||||
Biological Process | GO:0050863 | regulation of T cell activation | IGI | J:226998 | |||||||||
Biological Process | GO:0032680 | regulation of tumor necrosis factor production | IMP | J:207137 | |||||||||
Biological Process | GO:0032479 | regulation of type I interferon production | IGI | J:226998 | |||||||||
Biological Process | GO:0032479 | regulation of type I interferon production | IMP | J:166550 | |||||||||
Biological Process | GO:0032479 | regulation of type I interferon production | IMP | J:202906 | |||||||||
Biological Process | GO:0009411 | response to UV | IMP | J:243357 | |||||||||
Biological Process | GO:0032197 | retrotransposition | IMP | J:251493 | |||||||||
Biological Process | GO:0002457 | T cell antigen processing and presentation | IMP | J:207137 | |||||||||
Biological Process | GO:0060337 | type I interferon-mediated signaling pathway | IMP | J:243357 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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