GO Annotations Graph

• Symbol: Pkp1
• Name: plakophilin 1
• ID: MGI:1328359

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0005521	lamin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:124009
Molecular Function	GO:0005515	protein binding	IPI	J:87593
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0001533	cornified envelope	IDA	J:230728
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0030057	desmosome	IDA	J:148138
Cellular Component	GO:1990124	messenger ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0007043	cell-cell junction assembly	IBA	J:265628
Biological Process	GO:0045110	intermediate filament bundle assembly	ISO	J:164563
Biological Process	GO:0045110	intermediate filament bundle assembly	IBA	J:265628
Biological Process	GO:1902373	negative regulation of mRNA catabolic process	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563