GO Annotations Graph

• Symbol: Cdk9
• Name: cyclin dependent kinase 9
• ID: MGI:1328368

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097322	7SK snRNA binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	IDA	J:230626
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IDA	J:191206
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	ISO	J:101015
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:206891
Molecular Function	GO:0005515	protein binding	IPI	J:245360
Molecular Function	GO:0005515	protein binding	IPI	J:228418
Molecular Function	GO:0005515	protein binding	IPI	J:201465
Molecular Function	GO:0005515	protein binding	IPI	J:278445
Molecular Function	GO:0005515	protein binding	IPI	J:190041
Molecular Function	GO:0005515	protein binding	IPI	J:165999
Molecular Function	GO:0005515	protein binding	IPI	J:191206
Molecular Function	GO:0005515	protein binding	IPI	J:191206
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0005515	protein binding	IPI	J:185950
Molecular Function	GO:0005515	protein binding	IPI	J:182882
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	IDA	J:192997
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:182882
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	ISO	J:164563
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	IBA	J:265628
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	IMP	J:183914
Molecular Function	GO:0017069	snRNA binding	IDA	J:101015
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:164497
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	TAS	J:164497
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	ISO	J:164563
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	IDA	J:199171
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:185950
Cellular Component	GO:0005634	nucleus	IDA	J:101015
Cellular Component	GO:0070691	P-TEFb complex	ISO	J:164563
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0008023	transcription elongation factor complex	ISO	J:164563
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0120186	negative regulation of protein localization to chromatin	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043923	positive regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:155856
Biological Process	GO:0120187	positive regulation of protein localization to chromatin	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:101015
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0006282	regulation of DNA repair	ISO	J:164563
Biological Process	GO:0031056	regulation of histone modification	ISO	J:164563
Biological Process	GO:0031440	regulation of mRNA 3'-end processing	IMP	J:217992
Biological Process	GO:0031440	regulation of mRNA 3'-end processing	ISO	J:164563
Biological Process	GO:0051147	regulation of muscle cell differentiation	ISO	J:164563
Biological Process	GO:0031297	replication fork processing	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563