GO Annotations Graph

• Symbol: Dnase2a
• Name: deoxyribonuclease II alpha
• ID: MGI:1329019

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004531	deoxyribonuclease II activity	IBA	J:265628
Molecular Function	GO:0004531	deoxyribonuclease II activity	IDA	J:69831
Molecular Function	GO:0004520	DNA endonuclease activity	ISO	J:155856
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Cellular Component	GO:0005764	lysosome	TAS	J:69831
Biological Process	GO:0006309	apoptotic DNA fragmentation	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006308	DNA catabolic process	IMP	J:141401
Biological Process	GO:0006308	DNA catabolic process	IMP	J:94874
Biological Process	GO:0006259	DNA metabolic process	IEA	J:72247
Biological Process	GO:0043353	enucleate erythrocyte differentiation	IMP	J:69831
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050776	regulation of immune response	IGI	J:226998