GO Annotations Graph

• Symbol: Tcap
• Name: titin-cap
• ID: MGI:1330233

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0036122	BMP binding	ISO	J:164563
Molecular Function	GO:0051373	FATZ binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:80992
Molecular Function	GO:0005515	protein binding	IPI	J:76056
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IBA	J:265628
Molecular Function	GO:0008307	structural constituent of muscle	ISO	J:164563
Molecular Function	GO:0008307	structural constituent of muscle	IBA	J:265628
Molecular Function	GO:0031432	titin binding	ISO	J:164563
Molecular Function	GO:0031432	titin binding	IBA	J:265628
Molecular Function	GO:0070080	titin Z domain binding	ISO	J:164563
Molecular Function	GO:0070080	titin Z domain binding	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031674	I band	IDA	J:51067
Cellular Component	GO:1990733	titin-telethonin complex	ISO	J:164563
Cellular Component	GO:0030018	Z disc	IDA	J:51067
Cellular Component	GO:0030018	Z disc	ISO	J:164563
Cellular Component	GO:0030018	Z disc	IBA	J:265628
Biological Process	GO:0007512	adult heart development	ISO	J:164563
Biological Process	GO:0007512	adult heart development	IEP	J:51067
Biological Process	GO:0055013	cardiac muscle cell development	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	ISO	J:164563
Biological Process	GO:0060048	cardiac muscle contraction	IBA	J:265628
Biological Process	GO:0003300	cardiac muscle hypertrophy	ISO	J:164563
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	ISO	J:164563
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	ISO	J:164563
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	IBA	J:265628
Biological Process	GO:0055003	cardiac myofibril assembly	ISO	J:164563
Biological Process	GO:0055003	cardiac myofibril assembly	IBA	J:265628
Biological Process	GO:0035995	detection of muscle stretch	ISO	J:164563
Biological Process	GO:0035995	detection of muscle stretch	IBA	J:265628
Biological Process	GO:0030916	otic vesicle formation	IEP	J:51067
Biological Process	GO:0045214	sarcomere organization	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	ISO	J:51067
Biological Process	GO:0048769	sarcomerogenesis	ISO	J:164563
Biological Process	GO:0048769	sarcomerogenesis	IBA	J:265628
Biological Process	GO:0003009	skeletal muscle contraction	IBA	J:265628
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	ISO	J:164563
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	IBA	J:265628
Biological Process	GO:0030240	skeletal muscle thin filament assembly	ISO	J:164563
Biological Process	GO:0030240	skeletal muscle thin filament assembly	IBA	J:265628
Biological Process	GO:0001756	somitogenesis	IEP	J:51067