GO Annotations Graph

• Symbol: Cops2
• Name: COP9 signalosome subunit 2
• ID: MGI:1330276

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:219109
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0005515	protein binding	IPI	J:50270
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:87883
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0008180	COP9 signalosome	IBA	J:265628
Cellular Component	GO:0008180	COP9 signalosome	IDA	J:50270
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:219109
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:83134
Biological Process	GO:0001833	inner cell mass cell proliferation	IMP	J:85761
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:87883
Biological Process	GO:1903507	negative regulation of nucleic acid-templated transcription	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0030182	neuron differentiation	ISO	J:155856
Biological Process	GO:0000338	protein deneddylation	ISO	J:164563
Biological Process	GO:0000338	protein deneddylation	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0001834	trophectodermal cell proliferation	IMP	J:85761