GO Annotations Graph

• Symbol: Trp63
• Name: transformation related protein 63
• ID: MGI:1330810

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:107400
Molecular Function	GO:0003682	chromatin binding	IDA	J:107400
Molecular Function	GO:0003684	damaged DNA binding	IDA	J:116176
Molecular Function	GO:0003677	DNA binding	IDA	J:104687
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:177729
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:178430
Molecular Function	GO:0042802	identical protein binding	IPI	J:201295
Molecular Function	GO:0097371	MDM2/MDM4 family protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:157365
Molecular Function	GO:0005515	protein binding	IPI	J:201295
Molecular Function	GO:0005515	protein binding	IPI	J:168373
Molecular Function	GO:0005515	protein binding	IPI	J:199282
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:137734
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IEA	J:72247
Molecular Function	GO:0050699	WW domain binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:135784
Cellular Component	GO:0005634	nucleus	IDA	J:197352
Cellular Component	GO:0005634	nucleus	IDA	J:182873
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:122531
Cellular Component	GO:0005634	nucleus	IDA	J:121517
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:94980
Cellular Component	GO:0005634	nucleus	ISO	J:66126
Cellular Component	GO:0005634	nucleus	IDA	J:94647
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:71053
Cellular Component	GO:0005634	nucleus	IDA	J:71053
Cellular Component	GO:0005634	nucleus	IDA	J:133456
Cellular Component	GO:0005634	nucleus	IDA	J:105284
Cellular Component	GO:0005634	nucleus	IDA	J:87781
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:99962
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:79340
Cellular Component	GO:0005634	nucleus	IDA	J:66126
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:127939
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:54637
Biological Process	GO:0006915	apoptotic process	TAS	J:86247
Biological Process	GO:0090398	cellular senescence	IMP	J:100483
Biological Process	GO:0006338	chromatin remodeling	IMP	J:177729
Biological Process	GO:0060197	cloacal septation	IMP	J:79340
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:238904
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:238904
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:100483
Biological Process	GO:0032502	developmental process	IEA	J:72247
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0007499	ectoderm and mesoderm interaction	IMP	J:54636
Biological Process	GO:0007499	ectoderm and mesoderm interaction	IMP	J:54637
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:238904
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:238904
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:238904
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:238904
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:54636
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:135784
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:135784
Biological Process	GO:0009913	epidermal cell differentiation	IMP	J:238904
Biological Process	GO:0010481	epidermal cell division	IMP	J:186971
Biological Process	GO:0008544	epidermis development	IMP	J:181275
Biological Process	GO:0008544	epidermis development	IMP	J:54636
Biological Process	GO:0002064	epithelial cell development	IMP	J:186971
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:79340
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:127939
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:79340
Biological Process	GO:0001736	establishment of planar polarity	IDA	J:87781
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:203995
Biological Process	GO:0048807	female genitalia morphogenesis	IMP	J:79340
Biological Process	GO:0001942	hair follicle development	IMP	J:238904
Biological Process	GO:0001942	hair follicle development	IMP	J:104733
Biological Process	GO:0031069	hair follicle morphogenesis	IMP	J:107400
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:116176
Biological Process	GO:0030216	keratinocyte differentiation	IDA	J:87781
Biological Process	GO:0043616	keratinocyte proliferation	IGI	J:203995
Biological Process	GO:0001738	morphogenesis of a polarized epithelium	IMP	J:95347
Biological Process	GO:0007275	multicellular organism development	TAS	J:86247
Biological Process	GO:2000773	negative regulation of cellular senescence	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	IMP	J:220326
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	IMP	J:181275
Biological Process	GO:2000381	negative regulation of mesoderm development	IMP	J:186971
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:199282
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:105512
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:181275
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:104733
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:107400
Biological Process	GO:0007389	pattern specification process	IMP	J:54637
Biological Process	GO:0030859	polarized epithelial cell differentiation	IMP	J:95347
Biological Process	GO:0030859	polarized epithelial cell differentiation	IMP	J:95347
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	IDA	J:50106
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	ISO	J:164563
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	IGI	J:203995
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IMP	J:181275
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:1904674	positive regulation of somatic stem cell population maintenance	IMP	J:220326
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:203995
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:182873
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:50106
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:177729
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:135784
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:137734
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:199282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:99215
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:135784
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:79340
Biological Process	GO:0030850	prostate gland development	IMP	J:66126
Biological Process	GO:0060513	prostatic bud formation	IMP	J:66126
Biological Process	GO:0051262	protein tetramerization	IEA	J:72247
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:54636
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:133456
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010482	regulation of epidermal cell division	IMP	J:203995
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:54637
Biological Process	GO:0098773	skin epidermis development	IMP	J:238904
Biological Process	GO:0098773	skin epidermis development	IMP	J:238904
Biological Process	GO:0043589	skin morphogenesis	IMP	J:116077
Biological Process	GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	IMP	J:93615
Biological Process	GO:0048863	stem cell differentiation	IMP	J:93615
Biological Process	GO:0072089	stem cell proliferation	IGI	J:203995
Biological Process	GO:0072089	stem cell proliferation	IMP	J:238904
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:105512
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:135784
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:135784
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:99215
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:199282
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:137734