GO Annotations Graph

• Symbol: Lgmn
• Name: legumain
• ID: MGI:1330838

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IMP	J:227814
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:259127
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:155856
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IDA	J:50324
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IMP	J:85207
Molecular Function	GO:0008233	peptidase activity	ISO	J:73065
Cellular Component	GO:0045177	apical part of cell	IDA	J:85207
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:85207
Cellular Component	GO:0005764	lysosome	IDA	J:50324
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0008306	associative learning	IGI	J:227814
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:164563
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	ISO	J:164563
Biological Process	GO:0097061	dendritic spine organization	IGI	J:227814
Biological Process	GO:0007613	memory	IGI	J:227814
Biological Process	GO:1901185	negative regulation of ERBB signaling pathway	IMP	J:172774
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0040015	negative regulation of multicellular organism growth	IMP	J:85207
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:73065
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	ISO	J:164563
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IGI	J:227814
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IDA	J:50324
Biological Process	GO:0006508	proteolysis	IDA	J:85207
Biological Process	GO:0006508	proteolysis	IMP	J:136644
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	IMP	J:121440
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	IBA	J:265628
Biological Process	GO:0032801	receptor catabolic process	IMP	J:172774
Biological Process	GO:0003014	renal system process	IMP	J:172774
Biological Process	GO:0010447	response to acidic pH	IMP	J:227814
Biological Process	GO:0010447	response to acidic pH	ISO	J:164563
Biological Process	GO:0010447	response to acidic pH	IMP	J:136644
Biological Process	GO:0097264	self proteolysis	ISO	J:164563
Biological Process	GO:0006624	vacuolar protein processing	IBA	J:265628