GO Annotations Graph

• Symbol: Atp8a1
• Name: ATPase phospholipid transporting 8A1
• ID: MGI:1330848

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IBA	J:265628
Molecular Function	GO:0000287	magnesium ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0140346	phosphatidylserine flippase activity	IMP	J:281243
Molecular Function	GO:0140346	phosphatidylserine flippase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:273543
Molecular Function	GO:0005515	protein binding	IPI	J:197107
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:255476
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:281243
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031090	organelle membrane	IDA	J:296078
Cellular Component	GO:1990531	phospholipid-translocating ATPase complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:255476
Cellular Component	GO:0045202	synapse	IDA	J:255476
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IBA	J:265628
Biological Process	GO:0140331	aminophospholipid translocation	ISO	J:164563
Biological Process	GO:0140331	aminophospholipid translocation	IMP	J:281243
Biological Process	GO:0007612	learning	IMP	J:179412
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0045332	phospholipid translocation	IBA	J:265628
Biological Process	GO:0015914	phospholipid transport	IEA	J:72247
Biological Process	GO:0030335	positive regulation of cell migration	IMP	J:197107
Biological Process	GO:0061092	positive regulation of phospholipid translocation	IDA	J:179412