GO Annotations Graph

• Symbol: Epn2
• Name: epsin 2
• ID: MGI:1333766

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Cellular Component	GO:0030128	clathrin coat of endocytic vesicle	ISO	J:155856
Cellular Component	GO:0030125	clathrin vesicle coat	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0048568	embryonic organ development	IGI	J:151951
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0001701	in utero embryonic development	IGI	J:151951
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:151951
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0030100	regulation of endocytosis	ISO	J:155856